The purpose of this study is to examine the effectiveness of Collaborative Language Systems Therapy on Self- efficacy in Students .Method of research was quasi-experimental with pretest - posttest and control group design. The statistical population involved all referred couples to university counseling centers in Tehran. The sample of study consisted of 28 subjects(14 couples)that were randomly selected and allocated into experimental and control groupe.The experimental group participated in 8 sessions of collaborative Language Therapy. The measurement instrument was Coping self–Efficacy Scale (CSE) and Demographic Data Questionnaire. The results were analyzed with covariate using SPSS software. The result indicated that Collaborative Language Systems (CLST) Therapy, increased self-efficacy and enhanced subscales of Self-efficacy.